History of the Laboratory
Prof. Dr. Sinan Akgöl founded the Biochemistry Research Group in 2005, initially focusing on the development of specific adsorbents for the purification of biomolecules from their natural environments. Over the years, the isolation and purification of biomolecules—including proteins, enzymes, antibodies, nucleic acids, and hormones—have become increasingly significant in biotechnology, biochemistry, pharmacy, and medical sciences. Within this field, affinity-based separation techniques have gained particular prominence due to their high selectivity.
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From its early years, the group pioneered the design and development of monodisperse nano- and microspheres, macrospheres, membranes, and magnetic carriers, tailoring these materials for diverse applications such as protein purification and the removal of toxic substances. The group’s research further expanded into exploring the applicability of polymeric nanosorbents across bioseparation, sensor development, and biomolecule isolation.
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In recent years, the laboratory has embraced new scientific directions by integrating artificial intelligence-assisted nanobiosensors and applying machine learning techniques to enhance separation, purification, and isolation processes. This transformation reflects the group’s vision of combining polymeric nanotechnology with data-driven approaches to address complex biomedical and biotechnological challenges.
In 2023, recognizing the transformative role of artificial intelligence in data processing and advanced bioengineering, Prof. Dr. Akgöl redefined the group’s mission and renamed it the “Biorege Polymeric Nanosystems & AI Assisted Applications Laboratory.” This restructuring also brought AI specialists into the team, strengthening its interdisciplinary profile and positioning the laboratory at the forefront of research that bridges polymer science and artificial intelligence.
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Today, the laboratory consists of a vibrant and interdisciplinary team of postdoctoral researchers, Ph.D. candidates, and M.Sc. students working across polymer science, sensor technologies, molecular modeling, histology & embryology, and artificial intelligence. With more than 145 scientific publications, 3,500 citations, 9 patents, and 140 international conference presentations, as well as the successful supervision of 19 M.Sc. and 11 Ph.D. theses, the laboratory continues to build on its strong legacy of innovation and excellence. According to Google Scholar, Prof. Dr. Akgöl holds an h-index of 37.




